سال انتشار: 2021
تعداد صفحات: 216
زبان فایل: انگلیسی
فرمت فایل: pdf
حجم فایل: 6MB
ناشر: Wiley-VCH
ISBN-10 : 3527347283
ISBN-13 : 978-3527347285
ASIN : B08VFBKHDW
This authoritative overview on an emerging topic in the molecular life sciences covers all aspects of the aging of (long-lived) proteins. It describes the molecular mechanisms of aging on the protein level, in particular the most common side chain modifications and includes analytical methods to study protein half-life and the accumulation of modifications. Finally, the impact of protein aging on several age-related disases in humans is dissected, and their role in limiting human lifespan is discussed.